Components of pharmacist-led medication reviews and their relationship to outcomes: A systematic review and narrative synthesis

Craske, Miriam E., Hardeman, Wendy ORCID: https://orcid.org/0000-0002-6498-9407, Steel, Nicholas ORCID: https://orcid.org/0000-0003-1528-140X and Twigg, Michael J. ORCID: https://orcid.org/0000-0003-0910-3850 (2024) Components of pharmacist-led medication reviews and their relationship to outcomes: A systematic review and narrative synthesis. BMJ Quality & Safety. ISSN 2044-5415

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Abstract

Introduction: Pharmacist-led medication reviews are an established intervention to support patients prescribed multiple medicines or with complex medication regimes. For this systematic review (registered in PROSPERO, CRD42020173907), a medication review was defined as “a consultation between a pharmacist and a patient to review the patient’s total medicines use with a view to improve patient health outcomes and minimise medicines related problems”. It is not known how varying approaches to medication reviews lead to different outcomes. Aim: To explore the common themes associated with positive outcomes from pharmacist-led medication reviews. Method: Randomised controlled trials of pharmacist-led medication reviews in adults aged 18 and over were included. The search terms used in MEDLINE, EMBASE and Web of Science databases were “medication review”, “pharmacist”, “randomised controlled trial” and their synonyms, time filter 2015 to September 2023. Studies published before 2015 were identified from a previous systematic review. Risk of bias was assessed using the Cochrane risk of bias 2 tool. Descriptions of medication reviews’ components, implementation and outcomes were narratively synthesised to draw out common themes. Results are presented in tables. Results: Sixty-eight papers describing 50 studies met the inclusion criteria. Common themes that emerged from synthesis include collaborative working which may help reduce medicines-related problems and the number of medicines prescribed; patient involvement in goal setting and action planning which may improve patients’ ability to take medicines as prescribed and help them achieve their treatment goals; additional support and follow up, which may lead to improved blood pressure, diabetes control, quality of life and a reduction of medicines-related problems. Conclusion: This systematic review identified common themes and components, e.g., goal setting, action planning, additional support and follow up, that may influence outcomes of pharmacist-led medication reviews. Researchers, health professionals and commissioners could use these for a comprehensive evaluation of medication review implementation.

Item Type: Article
Additional Information: Data availability statement: All data relevant to the study are included in the article or uploaded as supplementary information.
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Science > School of Pharmacy
Faculty of Medicine and Health Sciences > School of Health Sciences
Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Faculty of Medicine and Health Sciences > Research Groups > Behavioural and Implementation Science
Faculty of Medicine and Health Sciences > Research Groups > Health Promotion
Faculty of Science > Research Groups > Patient Care
Depositing User: LivePure Connector
Date Deposited: 02 Jul 2024 08:34
Last Modified: 19 Jul 2024 14:31
URI: https://ueaeprints.uea.ac.uk/id/eprint/95742
DOI: 10.1136/bmjqs-2024-017283

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