Saying a firm 'no' to DNA re-replication

Blow, J. Julian and Prokhorova, Tatyana A. (1999) Saying a firm 'no' to DNA re-replication. Nature Cell Biology, 1 (7). E175-E177. ISSN 1465-7392

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Yeast cells exclude the DNA-replication-initiation factor Mcm4 from the nucleus during the S and G2 phases of the cell cycle, when active replication ‘origins’ must not reassemble. This exclusion is dependent on cyclin-dependent kinases and provides a general mechanism for preventing re-replication of DNA in a single cell cycle.

Item Type: Article
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Depositing User: LivePure Connector
Date Deposited: 10 Jun 2024 16:30
Last Modified: 10 Jun 2024 16:30
DOI: 10.1038/15611

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