A new role for Ran in ensuring precise duplication of chromosomal DNA

Blow, J. Julian (2003) A new role for Ran in ensuring precise duplication of chromosomal DNA. Cell, 113 (1). pp. 2-4. ISSN 0092-8674

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Abstract

To prevent re-replication of DNA, the licensing of replication origins is inhibited in S phase and G2. New work by Yamaguchi et al. (in this issue of Cell) shows that the small GTPase Ran can directly inhibit licensing inside nuclei once CDKs are active late in the cell cycle.

Item Type: Article
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Depositing User: LivePure Connector
Date Deposited: 10 Jun 2024 16:30
Last Modified: 10 Jun 2024 16:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/95516
DOI: 10.1016/S0092-8674(03)00236-8

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