Gillespie, Peter J., Li, Anatoliy and Blow, J. Julian (2001) Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins. BMC Biochemistry, 2. ISSN 1471-2091
Full text not available from this repository. (Request a copy)Abstract
In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes of Mcm2-7 onto them. Mcm2-7 are essential for DNA replication, but are displaced from origins as they initiate, thus ensuring that no origin fires more than once in a single cell cycle.
Item Type: | Article |
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Faculty \ School: | |
Depositing User: | LivePure Connector |
Date Deposited: | 10 Jun 2024 16:30 |
Last Modified: | 06 Feb 2025 12:00 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/95513 |
DOI: | 10.1186/1471-2091-2-15 |
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