Gillespie, Peter J., Li, Anatoliy and Blow, J. Julian ORCID: https://orcid.org/0000-0002-9524-5849
(2001)
Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins.
BMC Biochemistry, 2.
ISSN 1471-2091
Abstract
In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes of Mcm2-7 onto them. Mcm2-7 are essential for DNA replication, but are displaced from origins as they initiate, thus ensuring that no origin fires more than once in a single cell cycle.
Item Type: | Article |
---|---|
Faculty \ School: | |
Depositing User: | LivePure Connector |
Date Deposited: | 10 Jun 2024 16:30 |
Last Modified: | 22 Aug 2024 11:36 |
URI: | https://ueaeprints.uea.ac.uk/id/eprint/95513 |
DOI: | 10.1186/1471-2091-2-15 |
Actions (login required)
![]() |
View Item |