The regulation of replication origin activation

Donaldson, Anne D. and Blow, J. Julian ORCID: https://orcid.org/0000-0002-9524-5849 (1999) The regulation of replication origin activation. Current Opinion in Genetics and Development, 9 (1). pp. 62-68. ISSN 0959-437X

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Abstract

At the start of the cell-division programme, proteins must be assembled onto replication origins to establish competence for initiation of DNA synthesis. At the correct moment, other effectors must then coordinate appropriate firing of the various origins to control entry into and progress through S phase. These processes are key targets of cell-cycle control, and understanding their regulation will provide a deeper knowledge of the mechanisms controlling cell proliferation.

Item Type: Article
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Depositing User: LivePure Connector
Date Deposited: 10 Jun 2024 16:30
Last Modified: 23 Jul 2024 02:24
URI: https://ueaeprints.uea.ac.uk/id/eprint/95503
DOI: 10.1016/S0959-437X(99)80009-4

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