Noninvasive techniques for tracking biological aging of the cardiovascular system

Raisi-Estabragh, Zahra, Szabo, Liliana, Schuermans, Art, Salih, Ahmed M., Chin, Calvin W. L., Vágó, Hajnalka, Altmann, Andre, Ng, Fu Siong, Garg, Pankaj ORCID: https://orcid.org/0000-0002-5483-169X, Pavanello, Sofia, Marwick, Thomas H. and Petersen, Steffen E. (2024) Noninvasive techniques for tracking biological aging of the cardiovascular system. JACC: Cardiovascular Imaging. ISSN 1936-878X

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Abstract

Population aging is one of the most important demographic transformations of our time. Increasing the “health span”—the proportion of life spent in good health—is a global priority. Biological aging comprises molecular and cellular modifications over many years, which culminate in gradual physiological decline across multiple organ systems and predispose to age-related illnesses. Cardiovascular disease is a major cause of ill health and premature death in older people. The rate at which biological aging occurs varies across individuals of the same age and is influenced by a wide range of genetic and environmental exposures. The authors review the hallmarks of biological cardiovascular aging and their capture using imaging and other noninvasive techniques and examine how this information may be used to understand aging trajectories, with the aim of guiding individual- and population-level interventions to promote healthy aging.

Item Type: Article
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Metabolic Health
Depositing User: LivePure Connector
Date Deposited: 09 Apr 2024 12:30
Last Modified: 14 Apr 2024 23:54
URI: https://ueaeprints.uea.ac.uk/id/eprint/94881
DOI: 10.1016/j.jcmg.2024.03.001

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