Interplay between cell-surface receptor and intracellular NLR-mediated immune responses

Kourelis, Jiorgos ORCID: https://orcid.org/0000-0002-9007-1333 (2023) Interplay between cell-surface receptor and intracellular NLR-mediated immune responses. New Phytologist, 240 (6). pp. 2218-2226. ISSN 0028-646X

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Abstract

The functional link between cell-surface receptors and intracellular NLR immune receptors is a critical aspect of plant immunity. To establish disease, successful pathogens have evolved mechanisms to suppress cell-surface immune signalling. In response, plants have adapted by evolving NLRs that recognize pathogen effectors involved in this suppression, thereby counteracting their immune-suppressing function. This ongoing co-evolutionary struggle has seemingly resulted in intertwined signalling pathways in some plant species, where NLRs form a separate signalling branch downstream of activated cell-surface receptor complexes essential for full immunity. Understanding these interconnected receptor networks could lead to novel strategies for developing durable disease resistance.

Item Type: Article
Additional Information: Funding Information: I would like to acknowledge OpenAI's GPT‐4, as implemented in ChatGPT, for its assistance in the editing process. I would like to thank members of the Kamoun group for the discussions which shaped this review. In particular, I would like to thank Andres Posbeyikian, Daniel Lüdke, Lida Derevnina, and Hiroaki Adachi for critically reading the manuscript and providing comments. I would also like to thank Sophien Kamoun for encouragement in writing this review. JK is funded by BASF Plant Science. The funder had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Uncontrolled Keywords: cell-surface immunity,cellular signalling,intracellular nlr-mediated immunity,phosphorylation cascade,plant immunity,physiology,plant science ,/dk/atira/pure/subjectarea/asjc/1300/1314
Faculty \ School: Faculty of Science > The Sainsbury Laboratory
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Depositing User: LivePure Connector
Date Deposited: 07 Dec 2023 01:45
Last Modified: 01 Feb 2024 03:07
URI: https://ueaeprints.uea.ac.uk/id/eprint/93887
DOI: 10.1111/nph.19212

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