Comparing the symptomatology of post-stroke depression with depression in the general population: A systematic review

Blake, Josh J. ORCID:, Gracey, Fergus ORCID:, Whitmore, Shiona and Broomfield, Niall M. ORCID: (2023) Comparing the symptomatology of post-stroke depression with depression in the general population: A systematic review. Neuropsychology Review. ISSN 1040-7308

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Previous research into the phenomenological differences of post-stroke depression (PSD) has typically focused on comparisons of symptom profiles between stroke and non-stroke population controls. This systematic review aimed to synthesize these findings with results from other methodological approaches that contribute to an understanding of phenomenological differences. Articles were identified via a systematic search of seven databases and additional manual searching. A narrative synthesis approach was adopted because of the high methodological heterogeneity. Twelve articles comparing the symptomatology of depression between stroke and non-stroke controls were included. Three distinct methodological approaches, relevant to the aim, were identified: comparisons of profiles among groups with similar overall depression severity, comparisons of the strengths of correlations between a symptom and depression, and comparisons of latent symptom severity. The symptomatology of depression was generally similar between the groups, including somatic symptoms, despite the hypothesized interference of comorbid physical stroke effects. Despite high heterogeneity, there was a tentative indication that post-stroke depression manifests with comparatively less severe/prevalent anhedonia. Possible mechanisms for the observed similarities and differences are explored, including suggestions for future research.

Item Type: Article
Uncontrolled Keywords: post-stroke depression,phenomenology,symptomatology,stroke,systematic review,symptomatology,post-stroke depression,neuropsychology and physiological psychology ,/dk/atira/pure/subjectarea/asjc/3200/3206
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
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Depositing User: LivePure Connector
Date Deposited: 05 Sep 2023 14:30
Last Modified: 19 Oct 2023 03:39
DOI: 10.1007/s11065-023-09611-5


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