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Jegatheeswaran, Lavandan, Gokani, Shyam Ajay, Luke, Louis, Klyvyte, Gabija, Espehana, Andreas, Garden, Elizabeth Mairenn, Tarantino, Alessia, Al Omari, Basil and Philpott, Carl Martin 
ORCID: https://orcid.org/0000-0002-1125-3236
(2023)
Assessment of COVID-19-related olfactory dysfunction and its association with psychological, neuropsychiatric, and cognitive symptoms.
Frontiers in Neuroscience, 17.
ISSN 1662-4548
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Abstract
Purpose of review: To provide a detailed overview of the assessment of COVID-19-related olfactory dysfunction and its association with psychological, neuropsychiatric, and cognitive symptoms. Recent findings: COVID-19-related olfactory dysfunction can have a detrimental impact to the quality of life of patients. Prior to the COVID-19 pandemic, olfactory and taste disorders were a common but under-rated, under-researched and under-treated sensory loss. The pandemic has exacerbated the current unmet need for accessing good healthcare for patients living with olfactory disorders and other symptoms secondary to COVID-19. This review thus explores the associations that COVID-19 has with psychological, neuropsychiatric, and cognitive symptoms, and provide a framework and rationale for the assessment of patients presenting with COVID-19 olfactory dysfunction. Summary: Acute COVID-19 infection and long COVID is not solely a disease of the respiratory and vascular systems. These two conditions have strong associations with psychological, neuropsychiatric, and cognitive symptoms. A systematic approach with history taking and examination particularly with nasal endoscopy can determine the impact that this has on the patient. Specific olfactory disorder questionnaires can demonstrate the impact on quality of life, while psychophysical testing can objectively assess and monitor olfaction over time. The role of cross-sectional imaging is not yet described for COVID-19-related olfactory dysfunction. Management options are limited to conservative adjunctive measures, with some medical therapies described.
| Item Type: | Article |
|---|---|
| Additional Information: | Funding Information: CP reports grants from NIHR, ESPRC, and ENT UK, personal fees from Stryker, Abbott, and Olympus, outside the submitted work, and Trustee of Fifth Sense. |
| Uncontrolled Keywords: | anosmia,covid-19,hyposmia,olfaction,olfactory disorders,neuroscience(all) ,/dk/atira/pure/subjectarea/asjc/2800 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 04 Sep 2023 15:30 |
| Last Modified: | 29 Jan 2024 03:29 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/92982 |
| DOI: | 10.3389/fnins.2023.1165329 |
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