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Gokani, Shyam Ajay, Clark, Allan 
ORCID: https://orcid.org/0000-0003-2965-8941, Javer, Amin and Philpott, Carl ORCID: https://orcid.org/0000-0002-1125-3236
(2023)
Prevalence and associated factors of medication non-adherence in CRS patients following endoscopic sinus surgery.
Journal of Clinical Medicine, 12 (16).
ISSN 2077-0383
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Abstract
This study aimed to evaluate factors that may predispose patients to not adhere to prescribed medication after endoscopic sinus surgery (ESS) and to compare SNOT-22 scores at 0–12 months post-operatively between adherent and non-adherent patients. CRS patients who underwent ESS between 2012 and 2016 were recruited to this retrospective cohort study. Adherence was assessed through a questionnaire and review of medical notes. Ninety-four participants were included (61% male, mean age 60). Of those, 66% did not adhere to their prescribed post-operative CRS medication timing or dosage. The most common reason for non-adherence was improvement of symptoms (17%), followed by deterioration of symptoms (11%) and side effects (10%). Post-operative SNOT-22 scores were lowest for non-intentionally non-adherent (NINA) participants with a mean of 10.5 [95% CI: 7.47–13.5], compared to 25.0 for intentionally non-adherent (INA) [95% CI: 17.6–32.4] and 17.7 for adherent patients [95% CI: 13.7–21.7], p = 0.01. This study identifies that almost two-thirds of patients are not compliant with CRS medications after ESS. NINA participants reported lower post-operative SNOT-22 scores compared to INA and adherent participants. Future studies should focus on educating patients to continue with medications post-operatively despite an initial improvement in symptoms.
| Item Type: | Article |
|---|---|
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023) Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group Faculty of Medicine and Health Sciences > Research Centres > Population Health Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Depositing User: | LivePure Connector |
| Date Deposited: | 29 Aug 2023 08:30 |
| Last Modified: | 19 Oct 2023 03:38 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/92938 |
| DOI: | 10.3390/jcm12165381 |
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