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Lina-Dominguerz, Reyna, Penny, Mary, Kroon, Paul Antony, Burgos, Gabriela, Dainty, Jack 
ORCID: https://orcid.org/0000-0002-0056-1233, Zeder, Christophe, Zimmermann, Michael B., King, Janet, Mithen, Richard, Boy, Erick, Al-Jaiballi, Olla and Fairweather-Tait, Susan ORCID: https://orcid.org/0000-0002-1413-5569
(2023)
Biofortified yellow fleshed potatoes provide more absorbable zinc than a commonly consumed variety: a randomized trial using stable isotopes in women in the Peruvian highlands.
Journal of Nutrition, 153 (10).
pp. 2893-2900.
ISSN 0022-3166
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Abstract
Background: Zinc-biofortified potatoes have considerable potential to reduce zinc deficiency because of their low levels of phytate, an inhibitor of zinc absorption, and their high consumption, especially in the Andean region of Peru. Objectives: The purpose of this study was to measure fractional and total zinc absorption from a test meal of biofortified compared with regular potatoes. Methods: We undertook a single-blinded randomized crossover study (using 67Zn and 70Zn stable isotopes) in which 37 women consumed 500-g biofortified or regular potatoes twice a day. Urine samples were collected to determine fractional and total zinc absorption. Results: The zinc content of the biofortified potato and regular potato was 0.48 (standard deviation [SD]: 0.02) and 0.32 (SD: 0.03) mg/100 g fresh weight, respectively. Mean fractional zinc absorption (FZA) from the biofortified potatoes was lower than from the regular potatoes, 20.8% (SD: 5.4%) and 25.5% (SD: 7.0%), respectively (P < 0.01). However, total zinc absorbed was significantly higher (0.49; SD: 0.13 and 0.40; SD: 0.11 mg/500 g, P < 0.01, respectively). Conclusions: The results of this study demonstrate that biofortified potatoes provide more absorbable zinc than regular potatoes. Zinc-biofortified potatoes could contribute toward reducing zinc deficiency in populations where potatoes are a staple food. This trial was registered at clinicaltrials.gov as NCT05154500.
| Item Type: | Article |
|---|---|
| Additional Information: | Funding Information: This research was funded by the Biotechnology and Biological Sciences Research Council (BBSRC) through a Global Challenges Research Fund (GCRF) Grant (BB/S014039/1) and via the Institute Strategic Programme Grants ‘Food Innovation and Health’ (BB/R012512/1) and its constituent project BBS/E/F/000PR10343 and ‘Food Microbiome and Health’ (BB/X011054/1) and its constituent project BBS/E/F/000PR13630. We gratefully acknowledge USAID Feed the Future Crops to End Hunger award to CIP (DIS-B-AID-BFS-IO-17-00005). For the purpose of open access, the authors have applied a Creative Commons Attribution (CC BY) license to any Author Accepted Manuscript version arising. |
| Uncontrolled Keywords: | zinc absorption, biofortified crops, potatoes, stable isotopes,stable isotopes,potatoes,zinc absorption,biofortified crops,nutrition and dietetics,medicine (miscellaneous) ,/dk/atira/pure/subjectarea/asjc/2900/2916 |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| UEA Research Groups: | Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 29 Aug 2023 08:30 |
| Last Modified: | 04 Mar 2024 18:20 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/92937 |
| DOI: | 10.1016/j.tjnut.2023.08.028 |
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