AePUb promoter length modulates gene expression in Aedes aegypti

Anderson, Michelle A. E., Leftwich, Philip T. ORCID:, Wilson, Ray, Paladino, Leonela Z. Carabajal, Basu, Sanjay, Rooney, Sara, Adelman, Zach N. and Alphey, Luke (2023) AePUb promoter length modulates gene expression in Aedes aegypti.

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Molecular tools for modulating transgene expression in Aedes aegypti are few. Here we demonstrate that adjustments to the AePUb promoter length can alter expression levels of two reporter proteins in Ae. aegypti cell culture and in mosquitoes. This provides a simple means for increasing or decreasing expression of a gene of interest and easy translation from cells to whole insects.

Item Type: Article
Faculty \ School: Faculty of Science > School of Biological Sciences
UEA Research Groups: Faculty of Science > Research Groups > Biosciences Teaching and Education Research
Depositing User: LivePure Connector
Date Deposited: 15 Aug 2023 08:30
Last Modified: 15 Aug 2023 08:30
DOI: 10.1101/2023.08.11.553001

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