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Langdon, Peter E. 
ORCID: https://orcid.org/0000-0002-7745-1825, Harley, Carolyn W. and McLean, John H.
(1997)
Increased β adrenoceptor activation overcomes conditioned olfactory learning deficits induced by serotonin depletion.
Developmental Brain Research, 102 (2).
pp. 291-293.
Abstract
It was hypothesized that 5-HT2 receptors in the olfactory bulb prime the bulbar response to a β adrenoceptor mediated unconditioned stimulus (UCS) during odor preference learning in 1-week-old rat pups. The ability of 4 mg/kg of isoproterenol+stroking and 6 mg/kg of isoproterenol+no stroking to induce normal odor preference learning in pups depleted of bulbar 5-HT in the present study supports the hypothesis. The inverted-U curve relation between UCS strength and learning also appears to occur within the bulb.
| Item Type: | Article |
|---|---|
| Additional Information: | Acknowledgements: Supported by MRC of Canada Grant MT-10931 to J.H.M. and NSERC Grant 9791 to C.W.H. The authors wish to thank A. Darby-King and C.M. Whitt for their technical assistance. |
| Faculty \ School: | Faculty of Medicine and Health Sciences > Norwich Medical School |
| Depositing User: | LivePure Connector |
| Date Deposited: | 25 Jul 2023 09:30 |
| Last Modified: | 25 Jul 2023 09:30 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/92669 |
| DOI: | 10.1016/s0165-3806(97)00090-4 |
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