Lead-related complications after DDD pacemaker implantation

Debski, Maciej ORCID: https://orcid.org/0000-0002-3669-3916, Ulman, Mateusz, Zabek, Andrzej, Boczar, Krzysztof, Haberka, Kazimierz, Kuniewicz, Marcin, Lelakowski, Jacek and Malecka, Barbara (2018) Lead-related complications after DDD pacemaker implantation. Kardiologia polska, 76 (8). pp. 1224-1231.

Full text not available from this repository. (Request a copy)


Background: Pacing leads remain the weakest link in pacemaker systems despite advances in manufacturing technology. Aim: The aim of the study was to assess the long-term pacing lead performance in an unselected real-life cohort following primary DDD pacing system implantation. Methods: A single-centre retrospective analysis of patients who underwent DDD pacing system implantation between October 1984 and December 2014 and were followed-up until August 2016 was conducted. The inclusion criterion was at least one follow-up visit after post-implant discharge. The performance of each atrial and ventricular lead implanted was evaluated during the follow-up period, and the incidence of, and predictive factors for, lead dislodgement and failure were analysed. Results: The data of 3771 patients and 24,431.8 patient-years of follow-up were analysed. The mean follow-up of patients was 77.7 ± 61.8 months. During the study period, 7887 transvenous atrial and right ventricular pacing leads were implanted. Lead dislodgement occurred in 94 (1.2%) leads (92 [2.4%] patients), perforation in 11 (0.1%) leads (10 [0.3%] patients), and lead failure in 329 (4.2%) leads (275 [7.3%] patients). Atrial lead position was a predictive factor for lead dislodgement, while age at implantation, polyurethane 80A insulation, subclavian vein access, unipolar lead construction, and lead manufacturer were multivariate predictors of lead failure. Conclusions: Leads with polyurethane 80A insulation, unipolar construction, and those implanted via subclavian vein puncture exhibited the worst long-term performance.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 24 Jan 2023 14:30
Last Modified: 24 Jan 2023 14:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/90746
DOI: 10.5603/kp.a2018.0089

Actions (login required)

View Item View Item