No benefit of auditory closed-loop stimulation on memory for semantically-incongruent associations

Harrington, Marcus O. ORCID:, Ngo, Hong-Viet V. and Cairney, Scott A. (2021) No benefit of auditory closed-loop stimulation on memory for semantically-incongruent associations. Neurobiology of Learning and Memory, 183. ISSN 1074-7427

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Auditory closed-loop stimulation has gained traction in recent years as a means of enhancing slow oscillatory activity and, consequently, sleep-associated memory consolidation. Previous studies on this topic have primarily focused on the consolidation of semantically-congruent associations. In this study, we investigated the effect of auditory closed-loop stimulation on the overnight retention of semantically-incongruent associations. Twelve healthy males (age: M = 20.06, SD = 2.02 years) participated in two experimental conditions (simulation and sham). In the stimulation condition, clicks were delivered in phase with slow oscillation up-states, whereas in the sham condition no auditory stimuli were applied. Corroborating earlier work, stimulation (vs. sham) enhanced the slow oscillation rhythm, phase-coupled spindle activity and slow oscillation power. However, there was no benefit of stimulation on overnight memory retention. These findings suggest that closed-loop stimulation does not benefit semantically-incongruent associations.

Item Type: Article
Additional Information: Funding Information: This work was supported by Medical Research Council (MRC) Career Development Award MR/P020208/1 to S.A.C. Publisher Copyright: © 2021 Elsevier Inc.
Uncontrolled Keywords: declarative memory,semantic memory,slow-wave sleep,experimental and cognitive psychology,cognitive neuroscience,behavioral neuroscience ,/dk/atira/pure/subjectarea/asjc/3200/3205
Faculty \ School: Faculty of Social Sciences > School of Psychology
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Depositing User: LivePure Connector
Date Deposited: 16 Jan 2023 16:33
Last Modified: 16 Jan 2023 16:33
DOI: 10.1016/j.nlm.2021.107482

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