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Bowater, Richard 
ORCID: https://orcid.org/0000-0002-2745-7807
(2022)
DNA Structure and Replication.
MASSOLIT.
Abstract
About the Course: In this lecture, Professor Richard Bowater (University of East Anglia) talks about DNA, its structure, its replication and how it can code for proteins. To do so, we: (i) discuss the microscopic structure of DNA, looking at what each monomer (nucleotide) is made of; before (ii) understanding the history of its discovery and the macroscopic structure; following onto (iii) DNA polymerase and its role in DNA synthesis; which then goes on to (iv) the coding and non-coding sections of DNA and how four nucleotides code for 20 amino acids; before (v) diving into the step-by-step process of how new nucleotides are added to DNA; and then finally (vi) understanding how DNA can be mutated and damaged, and some of the implications this can have on the proteins it codes for. About the Lecturer: Having trained as a biochemist, Professor Richard Bowater's research interests broadened out to encompass methodologies that involve biophysical chemistry, microbiology, molecular biology and bioinformatics. His research focuses on macromolecular interactions of bacterial DNA repair proteins, particularly DNA and RNA ligases, with experiments performed in vitro or in bacterial model organisms. His areas of expertise include the relationship of genetic instabilities to human diseases; trinucleotide (triplet) repeat expansions and human neurodegenerative disorders; DNA repair processes; and protein-protein and protein-DNA interactions.
| Item Type: | Other |
|---|---|
| Uncontrolled Keywords: | sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being |
| Faculty \ School: | Faculty of Science > School of Biological Sciences |
| UEA Research Groups: | Faculty of Science > Research Groups > Molecular Microbiology Faculty of Science > Research Centres > Centre for Molecular and Structural Biochemistry |
| Related URLs: | |
| Depositing User: | LivePure Connector |
| Date Deposited: | 16 Nov 2022 00:54 |
| Last Modified: | 16 Nov 2022 00:54 |
| URI: | https://ueaeprints.uea.ac.uk/id/eprint/89871 |
| DOI: |
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