Investigations and outcomes for olfactory disorders

Luke, Louis, Lee, Liam, Jegatheeswaran, Lavandan and Philpott, Carl ORCID: (2022) Investigations and outcomes for olfactory disorders. Current Otorhinolaryngology Reports, 10 (4). 377–384. ISSN 2167-583X

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Purpose of Review: To provide a detailed overview of the investigations and core outcome measures for olfactory disorders. Recent Findings: Olfactory disorders can have a detrimental impact to the quality of life of patients. There are a wide range of causes of olfactory loss including sinonasal conditions, idiopathic, post-head trauma or infection. This review highlights the key investigations and reasoning for their use to clinically assess and research patients with olfactory disorders. In addition, this review outlines the core outcome measures for olfaction that will help inform future research in olfactory disorders. Summary: A systematic approach with history taking and examination particularly with nasal endoscopy can determine the cause of the olfactory disorder in most cases. Specific olfactory disorder questionnaires can demonstrate the impact on quality of life, while psychophysical testing can objectively assess and monitor olfaction over time. Olfactory-evoked potentials and functional MRI are reserved for research, whereas CT and MRI imaging are used depending on history and examination. A core outcome set for olfaction has been developed that will help standardise the outcome measures used in olfaction and olfactory disorders research.

Item Type: Article
Additional Information: Funding Information: CP reports grants from NIHR, ESPRC, and ENT UK; and personal fees from Stryker, Abbott, and Olympus, outside the submitted work; and Trustee of Fifth Sense. The other authors declare no competing interests.
Uncontrolled Keywords: anosmia,hyposmia,investigation,olfaction,olfactory disorders,outcome,surgery,immunology and allergy,otorhinolaryngology,clinical neurology ,/dk/atira/pure/subjectarea/asjc/2700/2746
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
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Depositing User: LivePure Connector
Date Deposited: 07 Nov 2022 12:30
Last Modified: 19 Oct 2023 03:28
DOI: 10.1007/s40136-022-00438-x


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