The evolving SARS-CoV-2 epidemic in Africa:Insights from rapidly expanding genomic surveillance

and Africa Pathogen Genomics Initiative (Africa PGI)‡ (2022) The evolving SARS-CoV-2 epidemic in Africa:Insights from rapidly expanding genomic surveillance. Science, 378 (6615). ISSN 0036-8075

[thumbnail of science.abq5358]
Preview
PDF (science.abq5358) - Published Version
Available under License Creative Commons Attribution.

Download (10MB) | Preview

Abstract

Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been generated and used to track the pandemic on the continent, a number that now exceeds 100,000 genomes. Our results show an increase in the number of African countries that are able to sequence domestically and highlight that local sequencing enables faster turnaround times and more-regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and illuminate the distinct dispersal dynamics of variants of concern-particularly Alpha, Beta, Delta, and Omicron-on the continent. Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve while the continent faces many emerging and reemerging infectious disease threats. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century.

Item Type: Article
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Science > School of Biological Sciences
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 04 Nov 2022 14:30
Last Modified: 21 Nov 2022 09:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/89620
DOI: 10.1126/science.abq5358

Actions (login required)

View Item View Item