Global prevalence of depression in HIV/AIDS: A systematic review and meta-analysis

Rezaei, Sepide, Ahmadi, Saba, Rahmati, Jeiran, Hosseinifard, Hossein, Dehnad, Afsaneh, Aryankhesal, Aidin ORCID:, Shabaninejad, Hosein, Ghasemyani, Shabnam, Alihosseini, Samira, Bragazzi, Nicola Luigi, Raoofi, Samira, Kiaee, Zahra Mansour and Ghashghaee, Ahmad (2019) Global prevalence of depression in HIV/AIDS: A systematic review and meta-analysis. BMJ Supportive and Palliative Care, 9 (4). pp. 404-412. ISSN 2045-435X

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Introduction: The incidence of some fatal diseases, including HIV/AIDS, accompanied by depression has become a significant concern in developed, developing and underdeveloped countries. A great deal of time and money are spent on controlling and reducing the complications of this infection across the world. Accordingly, the main purpose of this study was to clarify the global prevalence rate of depression in patients living with HIV/AIDS via a systematic review and meta-analysis. Methodology: All articles in English, published between 2000 and 2018, were systematically searched from the original databases of Web of Science, PubMed, Scopus, Cochrane Library, Google Scholar and Embase. As a result, a total of 118 articles were identified. Results: The total sample size in these articles was 51143 people, and the number of patients suffering from moderate and severe levels of depression was 14 942. The results of the analysis based on the random-effects (DerSimonian and Laird) model revealed that the prevalence rate of depression in patients with HIV/AIDS was 31% (95% CI 28% to 34%), with a 98% heterogeneity index which was reported significant. Meanwhile, the highest prevalence rate of depression based on continent was in South America at 44% (95% CI 35% to 53%) and the lowest rate was in Europe at 22% (95% CI 17% to 27%). Conclusion: In general, there was a higher prevalence rate of depression in developing and underdeveloped countries than in developed countries, which could be attributed to the advancement of science and the possibilities for early diagnosis of this syndrome. Trial registration number: CRD42019119137.

Item Type: Article
Additional Information: Publisher Copyright: © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Uncontrolled Keywords: depression,global,hiv,prevalence,systematic review & meta-analysis,medicine (miscellaneous),oncology(nursing),medical–surgical,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2701
Faculty \ School: Faculty of Medicine and Health Sciences > School of Health Sciences
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
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Depositing User: LivePure Connector
Date Deposited: 04 Nov 2022 09:30
Last Modified: 06 Jun 2024 15:21
DOI: 10.1136/bmjspcare-2019-001952

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