How to win a tug-of-war: the adaptive evolution of Phytophthora effectors

Dong, Suomeng and Ma, Wenbo (2021) How to win a tug-of-war: the adaptive evolution of Phytophthora effectors. Current Opinion in Plant Biology, 62. ISSN 1369-5266

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The ‘zigzag’ model formulates some of the fundamental principles underpinning the dynamic interactions between pathogen effectors and plant immunity. As key virulence factors, effectors often exhibit a pattern of rapid evolution, presumably as a result of the host-pathogen arms race. Here, we summarize the current knowledge of mechanisms that may accelerate effector evolution in the highly successful Phytophthora pathogens. Recent findings on epigenetic regulation of effector genes that allows evasion of host recognition and maintenance of cost/benefit balance, and a conserved structural unit in effector proteins that may promote the evolution of virulence activities are highlighted.

Item Type: Article
Additional Information: Funding Information: Authors would like to thank Kangping Li (Nanjing Agricultural University) for assistance in organizing the literature. Research on Phytophthora effectors in the W.M. group has been supported by National Science Foundation (NSF) grant IOS-1758889 , USDA-NIFA award # 2018-67014-28488, and the Gatsby Charitable Foundation . S.D. has been supported by grants from the Chinese National Science Fund ( 31972252 , 31721004 ). Publisher Copyright: © 2021 Elsevier Ltd
Uncontrolled Keywords: plant science ,/dk/atira/pure/subjectarea/asjc/1100/1110
Faculty \ School: Faculty of Science > The Sainsbury Laboratory
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Depositing User: LivePure Connector
Date Deposited: 13 Oct 2022 10:39
Last Modified: 20 Oct 2022 19:32
DOI: 10.1016/j.pbi.2021.102027

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