Small RNAs in plant immunity and virulence of filamentous pathogens

Qiao, Yongli, Xia, Rui, Zhai, Jixian, Hou, Yingnan, Feng, Li, Zhai, Yi and Ma, Wenbo (2021) Small RNAs in plant immunity and virulence of filamentous pathogens. Annual Review of Phytopathology, 59. pp. 265-288. ISSN 0066-4286

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Gene silencing guided by small RNAs governs a broad range of cellular processes in eukaryotes. Small RNAs are important components of plant immunity because they contribute to pathogen-triggered transcription reprogramming and directly target pathogen RNAs. Recent research suggests that silencing of pathogen genes by plant small RNAs occurs not only during viral infection but also in nonviral pathogens through a process termed host-induced gene silencing, which involves trans-species small RNA trafficking. Similarly, small RNAs are also produced by eukaryotic pathogens and regulate virulence. This review summarizes the small RNA pathways in both plants and filamentous pathogens, including fungi and oomycetes, and discusses their role in host-pathogen interactions. We highlight secondarysmall interfering RNAs of plants as regulators of immune receptor gene expression and executors of host-induced gene silencing in invading pathogens. The current status and prospects of trans-species gene silencing at the host-pathogen interface are discussed.

Item Type: Article
Additional Information: Funding Information: We apologize for being unable to discuss or cite all related studies because of limited space. Research in W.M.’s laboratory is supported by the National Science Foundation (IOS-1340001) and Gatsby Charity Foundation. The research in Y.Q.’s laboratory is supported by grants from the National Natural Science Foundation of China (32072502), the Shuguang Program of the Shanghai Education Development Foundation and Shanghai Municipal Education Commission (18SG43), and the Science and Technology Commission of Shanghai Municipality (18DZ2260500). We thank Dr. Michelle Hulin for her help with Figure 2. Publisher Copyright: Copyright © 2021 by Annual Reviews. All rights reserved.
Uncontrolled Keywords: gene silencing,host-pathogen arms race,nucleotidebinding leucine-rich repeat receptor,pentatricopeptide repeat protein,rna interference,small rna trafficking,medicine(all) ,/dk/atira/pure/subjectarea/asjc/2700
Faculty \ School: Faculty of Science > The Sainsbury Laboratory
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Depositing User: LivePure Connector
Date Deposited: 13 Oct 2022 10:39
Last Modified: 20 Oct 2022 19:32
DOI: 10.1146/annurev-phyto-121520-023514

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