Microbes, Human Milk, and Prebiotics

Kujawska, Magdalena, Collado, Maria Carmen and Hall, Lindsay J. ORCID: https://orcid.org/0000-0001-8938-5709 (2020) Microbes, Human Milk, and Prebiotics. In: The Human Microbiome in Early Life. Elsevier, pp. 197-237. ISBN 9780128180976

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Diet–microbe interactions play a crucial role in the early-life developmental window, exerting health effects in infancy that also extend to later life stages. Breastfeeding is the gold standard infant nutrition that is associated with healthy gut-associated microbial community development, optimal immune system maturation, and defense against pathogens. During early life, maternal breast milk “seeds” the neonate with milk-derived microbes, and acts as a natural prebiotic feeding certain bacterial strains and species, including members of genus Bifidobacterium. Benefits of breastfeeding are largely unavailable to infants fed with formula, therefore addition of prebiotics that can mimic functions of unique breast milk components, for example, human milk oligosaccharides (HMOs), is used to promote infant well-being. Later in infancy, complementary feeding during weaning provides essential nutrients and further prebiotic compounds, which promote the acquisition and colonization of a higher diversity of gut bacteria, enhancing bacterial production of beneficial metabolites, thus further supporting healthy infant development.

Item Type: Book Section
Additional Information: Publisher Copyright: © 2021 Elsevier Inc. All rights reserved.
Uncontrolled Keywords: immunology and microbiology(all) ,/dk/atira/pure/subjectarea/asjc/2400
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 03 Oct 2022 08:31
Last Modified: 14 Dec 2022 14:30
URI: https://ueaeprints.uea.ac.uk/id/eprint/88790
DOI: 10.1016/B978-0-12-818097-6.00009-2

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