Structural insights into higher order assembly and function of the bacterial micro compartment protein PduA

Pang, Allan, Frank, Stefanie, Brown, Ian R., Warren, Martin J. ORCID: https://orcid.org/0000-0002-6028-6456 and Pickersgill, Richard W. (2014) Structural insights into higher order assembly and function of the bacterial micro compartment protein PduA. Journal of Biological Chemistry, 289 (32). pp. 22377-22384. ISSN 0021-9258

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Abstract

Background: PduA is a major shell protein in 1,2-propanediol utilization micro compartments. Results: The profound influence of Lys-26 and Arg-79 on hexagonal tiling is revealed both in the crystal and in vivo. Conclusion: Interactions seen in the crystal are important for sheet and nanotube assembly in the bacterial cytoplasm. Significance: This work provides knowledge for the engineering of PduA for stability and porosity for synthetic biology applications.

Item Type: Article
Uncontrolled Keywords: biochemistry,molecular biology,cell biology ,/dk/atira/pure/subjectarea/asjc/1300/1303
Faculty \ School: Faculty of Science
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Depositing User: LivePure Connector
Date Deposited: 20 Sep 2022 14:31
Last Modified: 24 Oct 2022 06:52
URI: https://ueaeprints.uea.ac.uk/id/eprint/88494
DOI: 10.1074/jbc.M114.569285

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