Bridging gaps in transposable element research with single-molecule and single-cell technologies

Kutter, Claudia, Jern, Patric and Suh, Alexander ORCID: https://orcid.org/0000-0002-8979-9992 (2018) Bridging gaps in transposable element research with single-molecule and single-cell technologies. Mobile DNA, 9 (1). ISSN 1759-8753

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Abstract

More than half of the genomic landscape in humans and many other organisms is composed of repetitive DNA, which mostly derives from transposable elements (TEs) and viruses. Recent technological advances permit improved assessment of the repetitive content across genomes and newly developed molecular assays have revealed important roles of TEs and viruses in host genome evolution and organization. To update on our current understanding of TE biology and to promote new interdisciplinary strategies for the TE research community, leading experts gathered for the 2nd Uppsala Transposon Symposium on October 4-5, 2018 in Uppsala, Sweden. Using cutting-edge single-molecule and single-cell approaches, research on TEs and other repeats has entered a new era in biological and biomedical research.

Item Type: Article
Additional Information: Funding Information: The 2ndUppsala Transposon was kindly supported by conference grants of the Swedish Research Council Vetenskapsrådet (2018–00767) and the Wenner-Gren Foundations (ESv2018–0014). Publisher Copyright: © 2018 The Author(s).
Uncontrolled Keywords: centromeres,endogenous viruses,evolution,long read-sequencing,repetitive sequence,satellites,transposable elements,molecular biology ,/dk/atira/pure/subjectarea/asjc/1300/1312
Faculty \ School: Faculty of Science > School of Biological Sciences
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 16 Sep 2022 13:37
Last Modified: 24 Sep 2022 07:15
URI: https://ueaeprints.uea.ac.uk/id/eprint/88400
DOI: 10.1186/s13100-018-0140-5

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