Isolation and genetic characterization of a coinfection of non-O157 Shiga toxin-producing Escherichia coli

Gilmour, Matthew W., Tabor, Helen, Wang, Gehua, Clark, Clifford G., Tracz, Dobryan M., Olson, Adam B., Mascarenhas, Mariola, Karmali, Mohamed A., Mailman, Tim and Ng, Lai King (2007) Isolation and genetic characterization of a coinfection of non-O157 Shiga toxin-producing Escherichia coli. Journal of Clinical Microbiology, 45 (11). pp. 3771-3773. ISSN 0095-1137

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Abstract

A coinfection of O177:NM and O55:H7 Shiga toxin-producing Escherichia coli (STEC) was identified for a child with acute bloody diarrhea and hemolytic uremic syndrome by using culture and serotype-specific molecular reagents. The profile of O157-related genetic islands revealed that the O55:H7 isolate was highly similar to O157 STEC whereas the O177:NM isolate lacked several fimbrial O islands and non-locus-of-enterocyte-effacement effector determinants. However, both STEC serotypes are known to cause serious disease, and the significant repertoire of virulence determinants in both strains made it impossible to determine their individual contributions to the clinical symptoms.

Item Type: Article
Uncontrolled Keywords: microbiology (medical),sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2726
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 14 Sep 2022 10:31
Last Modified: 30 Sep 2022 02:33
URI: https://ueaeprints.uea.ac.uk/id/eprint/88264
DOI: 10.1128/JCM.01125-07

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