Pretransfusion comparison of dialyser-based hemoconcentrator with cell saver system for perioperative cell salvage

Garg, Pankaj ORCID: https://orcid.org/0000-0002-5483-169X, Malhotra, Amber, Desai, Manan, Sharma, Pranav, Bishnoi, Arvind Kumar, Tripathi, Payal, Rodricks, Dayesh and Pandya, Himani (2015) Pretransfusion comparison of dialyser-based hemoconcentrator with cell saver system for perioperative cell salvage. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 10 (5). pp. 334-341. ISSN 1556-9845

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Abstract

Objective: Cell Saver system is the method of choice for red blood cell salvage from the surgical field; however, cost is a limiting factor. We at our institute have devised a cost-effective version of dialyser-based autotransfusion system. We performed pretransfusion comparison of our autotransfusion system with conventional cell saver system. Methods: Aprospective randomized observational studywas performed in 104 consecutive patients with coronary artery disease undergoing by off-pump coronary artery bypass grafting. Patients were divided into two groups. In the dialyser group (53 patients), blood from surgical field was salvaged by our dialyser-based system. In the cell saver group (51 patients), blood was salvaged by cell saver. In both groups, 20-mL sample from the salvaged blood was analyzed for hemoglobin, platelets, protein, albumin, free hemoglobin, osmotic fragility, and peripheral blood smear examination. Results: Total hemoglobin salvaged was comparable in both groups (85% vs 76%). On peripheral smear, red blood cells were swollen, but morphologywas preserved.Moreover, normal osmotic fragility suggested absence of any lethal damage to red blood cells in either group. Dialyserbased system was more efficient in salvaging platelets (42.9% vs 6%), proteins (79.2% vs 0%), and albumin (65% vs 0%). Total free hemoglobin was three times more in dialyser group but was well below recommended limits. Conclusions: Dialyser-based system is economical, is equally efficacious in salvaging red blood cells, is more effective in salvaging platelets and proteins, and does not contain significant amount of free hemoglobin. Therefore, this salvaged blood can be safely transfused.

Item Type: Article
Additional Information: Publisher Copyright: © 2015 by the International Society for Minimally Invasive Cardiothoracic Surgery.
Uncontrolled Keywords: autotransfusion,conventional cell saver,dialyser-based cell salvage,off-pump coronary bypass grafting,surgery,pulmonary and respiratory medicine,cardiology and cardiovascular medicine ,/dk/atira/pure/subjectarea/asjc/2700/2746
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 07 Sep 2022 13:30
Last Modified: 21 Oct 2022 01:36
URI: https://ueaeprints.uea.ac.uk/id/eprint/87838
DOI: 10.1097/IMI.0000000000000180

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