Longer-term use of electronic cigarettes when provided as a stop smoking aid: Systematic review with meta-analyses

Butler, Ailsa R., Lindson, Nicola, Fanshawe, Thomas R., Theodoulou, Annika, Begh, Rachna, Hajek, Peter, McRobbie, Hayden, Bullen, Chris, Notley, Caitlin ORCID: https://orcid.org/0000-0003-0876-3304, Rigotti, Nancy A. and Hartmann-Boyce, Jamie (2022) Longer-term use of electronic cigarettes when provided as a stop smoking aid: Systematic review with meta-analyses. Preventive Medicine, 165 (B). ISSN 0091-7435

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Moderate certainty evidence supports use of nicotine electronic cigarettes to quit smoking combustible cigarettes. However, there is less certainty regarding how long people continue to use e-cigarettes after smoking cessation attempts. We set out to synthesise data on the proportion of people still using e-cigarettes or other study products at 6 months or longer in studies of e-cigarettes for smoking cessation. We updated Cochrane searches (November 2021). For the first time, we meta-analysed prevalence of continued e-cigarette use among individuals allocated to e-cigarette conditions, and among those individuals who had successfully quit smoking. We updated meta-analyses comparing proportions continuing product use among individuals allocated to use nicotine e-cigarettes and other treatments. We included 19 studies (n = 7787). The pooled prevalence of continued e-cigarette use at 6 months or longer was 54% (95% CI: 46% to 61%, I2 86%, N = 1482) in participants assigned to e-cigarette conditions. Of participants who had quit combustible cigarettes overall 70% were still using e-cigarettes at six months or longer (95% CI: 53% to 82%, I2 73%, N = 215). Heterogeneity in direction of effect precluded meta-analysis comparing long-term use of nicotine e-cigarettes with NRT. More people were using nicotine e-cigarettes at longest follow-up compared to non-nicotine e-cigarettes, but CIs included no difference (risk ratio 1.15, 95% CI: 0.94 to 1.41, n = 601). The levels of continued e-cigarette use observed may reflect the success of e-cigarettes as a quitting tool. Further research is needed to establish drivers of variation in and implications of continued use of e-cigarettes.

Item Type: Article
Additional Information: Funding Information: This work was supported by funding from Cancer Research UK and an Oxford University Public Policy Challenge Grant.
Uncontrolled Keywords: e-cigarette,electronic cigarette,longer term use,quitting smoking,smoking cessation,systematic review,epidemiology,public health, environmental and occupational health ,/dk/atira/pure/subjectarea/asjc/2700/2713
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 09 Aug 2022 09:30
Last Modified: 15 Dec 2022 03:26
URI: https://ueaeprints.uea.ac.uk/id/eprint/87144
DOI: 10.1016/j.ypmed.2022.107182

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