Implant-based reconstruction following mastectomy in patients who have had a previous breast augmentation: Lessons from the National Multicenter Implant Breast Reconstruction Evaluation Study

Baker, Benjamin G., Sewart, Emma, Harvey, James and Potter, Shelley and Implant Breast Reconstruction Evaluation Study Steering Group and Breast Reconstruction Research Collaborative (2022) Implant-based reconstruction following mastectomy in patients who have had a previous breast augmentation: Lessons from the National Multicenter Implant Breast Reconstruction Evaluation Study. Plastic and Reconstructive Surgery, 149 (2). pp. 324-337. ISSN 0032-1052

Full text not available from this repository.

Abstract

Background: Breast augmentation is the most commonly performed cosmetic procedure, and increasingly women in this group present with breast cancer or request risk-reducing surgery, but their optimal management is unclear. The authors explored the clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction following previous augmentation and compared these with outcomes of patients who had not had cosmetic implants in the Implant Breast Reconstruction Evaluation (iBRA) Study. Methods: Patients undergoing immediate implant-based breast reconstruction were prospectively recruited from breast and plastic surgical units across the United Kingdom. Demographic, operative, and oncologic data, and information regarding complications within 3 postoperative months were collected. Patient-reported outcomes at 18 months were assessed using the BREAST-Q. The clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction with and without previous breast augmentation were compared. Results: A total of 2108 women were included in the iBRA Study, of whom 49 had undergone a previous augmentation. Women in the augmentation group were younger (median age, 45 years versus 50 years; p = 0.01), had a lower body mass index (22.8 kg/m2 versus 24.9 kg/m2; p < 0.01), and had smaller tumors (15 mm versus 25 mm; p = 0.01) than patients without augmentation. No differences were seen in operative technique between the groups. Complications at 3 months were similar in both groups and there were no significant differences in patient-reported outcomes at 18 months. Conclusions: The clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction following previous augmentation are consistent with those observed in the wider iBRA Study cohort, supporting the safety of this approach.

Item Type: Article
Additional Information: Funding Information: This work was funded by a National Institute for Health Research, Research for Patient Benefit Programme grant (PB-PG-0214-33065); pump-priming funding from the Association of Breast Surgery and the British Association of Plastic Reconstructive and Aesthetic Surgeons; and a Research Development Award from the Association of Breast Surgery (2019). Shelley Potter, Ph.D., F.H.E.A., F.R.C.S., N.I.H.R., is a National Institute for Health Research Clinician Scientist (CS-2016-16-019). This work was undertaken with the support of the Medical Research Council ConDuCT-II (Collaboration and innovation for Difficult and Complex randomized controlled Trials In Invasive procedures) Hub for Trials Methodology Research (MR/K025643/1) and the National Institute for Health Research Biomedical Research Centre at University Hospitals Bristol National Health Service Foundation Trust and the University of Bristol.
Uncontrolled Keywords: surgery,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2746
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 26 Jul 2022 13:30
Last Modified: 03 Nov 2022 16:36
URI: https://ueaeprints.uea.ac.uk/id/eprint/86882
DOI: 10.1097/prs.0000000000008713

Actions (login required)

View Item View Item