Implant-based reconstruction following mastectomy in patients who have had a previous breast augmentation: Lessons from the National Multicenter Implant Breast Reconstruction Evaluation Study

Baker, Benjamin G., Sewart, Emma, Harvey, James, Potter, Shelley and , Implant Breast Reconstruction Evaluation Study Steering Group an (2022) Implant-based reconstruction following mastectomy in patients who have had a previous breast augmentation: Lessons from the National Multicenter Implant Breast Reconstruction Evaluation Study. Plastic and Reconstructive Surgery, 149 (2). pp. 324-337. ISSN 0032-1052

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Abstract

Background: Breast augmentation is the most commonly performed cosmetic procedure, and increasingly women in this group present with breast cancer or request risk-reducing surgery, but their optimal management is unclear. The authors explored the clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction following previous augmentation and compared these with outcomes of patients who had not had cosmetic implants in the Implant Breast Reconstruction Evaluation (iBRA) Study. Methods: Patients undergoing immediate implant-based breast reconstruction were prospectively recruited from breast and plastic surgical units across the United Kingdom. Demographic, operative, and oncologic data, and information regarding complications within 3 postoperative months were collected. Patient-reported outcomes at 18 months were assessed using the BREAST-Q. The clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction with and without previous breast augmentation were compared. Results: A total of 2108 women were included in the iBRA Study, of whom 49 had undergone a previous augmentation. Women in the augmentation group were younger (median age, 45 years versus 50 years; p = 0.01), had a lower body mass index (22.8 kg/m2 versus 24.9 kg/m2; p < 0.01), and had smaller tumors (15 mm versus 25 mm; p = 0.01) than patients without augmentation. No differences were seen in operative technique between the groups. Complications at 3 months were similar in both groups and there were no significant differences in patient-reported outcomes at 18 months. Conclusions: The clinical and patient-reported outcomes of patients undergoing immediate implant-based breast reconstruction following previous augmentation are consistent with those observed in the wider iBRA Study cohort, supporting the safety of this approach.

Item Type: Article
Additional Information: Funding Information: This work was funded by a National Institute for Health Research, Research for Patient Benefit Programme grant (PB-PG-0214-33065); pump-priming funding from the Association of Breast Surgery and the British Association of Plastic Reconstructive and Aesthetic Surgeons; and a Research Development Award from the Association of Breast Surgery (2019). Shelley Potter, Ph.D., F.H.E.A., F.R.C.S., N.I.H.R., is a National Institute for Health Research Clinician Scientist (CS-2016-16-019). This work was undertaken with the support of the Medical Research Council ConDuCT-II (Collaboration and innovation for Difficult and Complex randomized controlled Trials In Invasive procedures) Hub for Trials Methodology Research (MR/K025643/1) and the National Institute for Health Research Biomedical Research Centre at University Hospitals Bristol National Health Service Foundation Trust and the University of Bristol.
Uncontrolled Keywords: surgery,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2746
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 26 Jul 2022 13:30
Last Modified: 12 Aug 2022 04:49
URI: https://ueaeprints.uea.ac.uk/id/eprint/86882
DOI: 10.1097/prs.0000000000008713

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