Cytogenetic abnormalities in human ependymomas

Stratton, M. R., Darling, J., Lantos, P. L., Cooper, C. S. ORCID: https://orcid.org/0000-0003-2013-8042 and Reeves, B. R. (1989) Cytogenetic abnormalities in human ependymomas. International Journal of Cancer, 44 (4). pp. 579-581. ISSN 0020-7136

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Abstract

The karyotypes of 4 human ependymomas have been determined. In one ependymoma, translocations involving chromosomes 9, 17 and 22 were observed together with the loss of the normal chromosome 17. A second ependymoma had many chromosomal alterations that included a translocation between chromosomes 1 and 2 and re‐arrangements involving chromosome 17. No major consistent alterations were detected in the remaining 2 cases. Our karyotypes do not resemble the few previously published karyotypes of ependymomas, but had features, such as the alterations involving chromosome 17, that were similar to those of other brain tumours in children.

Item Type: Article
Uncontrolled Keywords: oncology,cancer research,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2730
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 18 Jul 2022 17:31
Last Modified: 13 Aug 2022 02:25
URI: https://ueaeprints.uea.ac.uk/id/eprint/86557
DOI: 10.1002/ijc.2910440403

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