Ensuring the reliability of brominated flame retardant data on food and feed occurrence through harmonised analytical criteria and proficiency testing

Fernandes, Alwyn, Zwickel, Theresa and Schächtele, Alexander (2022) Ensuring the reliability of brominated flame retardant data on food and feed occurrence through harmonised analytical criteria and proficiency testing. Chemosphere, 286 (3). ISSN 0045-6535

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The volume of occurrence data on food and animal feed contaminants such as polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecanes (HBCDDs) is slowly increasing as more laboratories develop analytical capability. This data allows an evaluation of current background levels in different countries and regions and is also useful for estimating the health risk through dietary exposure and as evidence for the formulation of future control strategies. Existing data varies in the number of analytes reported and the quality measures applied. In order to ensure reliability and comparability, guidance on analytical criteria such as precision and trueness, limits of quantitation, recovery, positive identification, etc. is provided. These parameters are based on several years of collective experience and allow validation and regular quality control of analysis of individual PBDE congeners and HBCDD stereoisomers. The criteria-based approach also allows laboratories the flexibility to use different analytical methodologies and techniques for generating data. The effectiveness of this approach has been demonstrated by a successful proficiency testing scheme that has been used for a number of years and has attracted an increasing number of participants. The majority of participating laboratories (> 80 %) have been able to demonstrate performance within the 95% confidence interval (│z-score│≤ 2) and a further 10 % of laboratories demonstrated performance with a z-score of (2 <│z-score│< 3). The combined support of these guidance criteria backed by successful proficiency testing will ensure the reliability and comparability of results, in particular, to refine risk assessments and to help the formulation of regulatory policy.

Item Type: Article
Additional Information: Funding Information: The authors are grateful to the members of the Working Group on Brominated Contaminants of the EURL/NRL network for halogenated POPs in feed and food; Dzintars Zacs (Institute of Food Safety, Animal Health and Environment ?BIOR?, Latvia), Philippe Marchand (Laboratoire d'Etude des R?sidus et Contaminants dans les Aliments (LABERCA), France), Georges Scholl (Centre de Recherche Analytique et Technologique (CART), Belgium), Helge T Hove (The Institute of Marine Research (Norwegian NRL for Halogenated POPs in feed and food), Bergen, Norway), Ana?s V?nisseau (Laboratoire d'Etude des R?sidus et Contaminants dans les Aliments (LABERCA), France), Tatiana Cantillana (Swedish food Agency, Sweden), Thorsten Bernsmann (Chemisches und Veterin?runtersuchungsamt M?nsterland-Emscher-Lippe, M?nster, Germany), Sebastian Maszewski (Pa?stwowy Instytut Weterynaryjny, Pu?awy, Poland), Panu Rantakokko (National Institute for Health and Welfare, Helsinki, Finland), Leondios Leondiadis (National Center for Scientific Research (NCSR) ?Demokritos?, Athens, Greece), for initial discussions on this topic. The European Commission is acknowledged for financially supporting the work of the EURL. Publisher Copyright: © 2021 Elsevier Ltd
Uncontrolled Keywords: bfrs,hbcdd,inter-laboratory comparison,pbde,validated analysis,public health, environmental and occupational health,pollution,chemistry(all),health, toxicology and mutagenesis,environmental engineering,environmental chemistry,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2739
Faculty \ School: Faculty of Science > School of Environmental Sciences
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Depositing User: LivePure Connector
Date Deposited: 25 May 2022 15:33
Last Modified: 22 Oct 2022 18:32
URI: https://ueaeprints.uea.ac.uk/id/eprint/85160
DOI: 10.1016/j.chemosphere.2021.131921

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