Using high-resolution contact networks to evaluate SARS-CoV-2 transmission and control in large-scale multi-day events

Pung, Rachael, Firth, Josh A., Spurgin, Lewis G., Lee, Vernon J. and Kucharski, Adam J. and Singapore CruiseSafe working group, CMMID COVID-19 working group (2022) Using high-resolution contact networks to evaluate SARS-CoV-2 transmission and control in large-scale multi-day events. Nature Communications, 13. ISSN 2041-1723

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The emergence of highly transmissible SARS-CoV-2 variants has created a need to reassess the risk posed by increasing social contacts as countries resume pre-pandemic activities, particularly in the context of resuming large-scale events over multiple days. To examine how social contacts formed in different activity settings influences interventions required to control Delta variant outbreaks, we collected high-resolution data on contacts among passengers and crew on cruise ships and combined the data with network transmission models. We found passengers had a median of 20 (IQR 10–36) unique close contacts per day, and over 60% of their contact episodes were made in dining or sports areas where mask wearing is typically limited. In simulated outbreaks, we found that vaccination coverage and rapid antigen tests had a larger effect than mask mandates alone, indicating the importance of combined interventions against Delta to reduce event risk in the vaccine era.

Item Type: Article
Additional Information: Funding Information: R.P. acknowledges funding from the Singapore Ministry of Health. J.A.F. was supported by a research fellowship from Merton College and BBSRC (BB/S009752/1) and acknowledges funding from NERC (NE/S010335/1). A.J.K. was supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (grant 206250/Z/17/Z).
Uncontrolled Keywords: physics and astronomy(all),chemistry(all),biochemistry, genetics and molecular biology(all),sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/3100
Faculty \ School: Faculty of Science > School of Biological Sciences
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Depositing User: LivePure Connector
Date Deposited: 06 May 2022 03:58
Last Modified: 19 Aug 2023 00:47
DOI: 10.1038/s41467-022-29522-y


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