Epidemiology of asymptomatic pre-heart failure: A systematic review

Bergamasco, Aurore, Luyet-Déruaz, Anouk, Gollop, Nicholas D., Moride, Yola and Qiao, Qing (2022) Epidemiology of asymptomatic pre-heart failure: A systematic review. Current Heart Failure Reports, 19 (3). pp. 146-156. ISSN 1546-9530

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Purpose of Review: To quantify the prevalence of asymptomatic pre-heart failure (pre-HF), progression to more severe stages, and associated mortality. Recent Findings: A systematic review was conducted between 01 January 2010 and 12 March 2020 (PROSPERO: CRD42020176141). Data of interest included prevalence, disease progression, and mortality rates. In total, 1030 sources were identified, of which, 12 reported on pre-HF (using the ACC/AHA definition for stage B HF) and were eligible. Prevalence estimates of pre-HF ranged from 11 to 42.7% (10 sources) with higher estimates found in the elderly, in patients with hypertension, and in men. Three studies reported on disease progression with follow-up ranging from 13 months to 7 years. The incidence of symptomatic HF (HF/advanced HF) ranged from 0.63 to 9.8%, and all-cause mortality from 1.6 to 5.4%. Summary: Further research is required to investigate whether early detection and intervention can slow or stop the progression from asymptomatic to symptomatic HF.

Item Type: Article
Additional Information: Funding Information: This study was supported by the Boehringer Ingelheim International GmbH. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Boehringer Ingelheim International GmbH. Editorial assistance was provided by the Nikita Vekaria of Envision Pharma Group (Wilmslow, UK), during the preparation of this article. Special thanks go to Jean-François Nepveu for his contribution to the manuscript. The editor would like to thank Dr. Christiane Angermann for taking the time to review this manuscript. Publisher Copyright: © 2022, The Author(s).
Uncontrolled Keywords: disease progression,mortality,prevalence,stage b heart failure,emergency medicine,cardiology and cardiovascular medicine,physiology (medical) ,/dk/atira/pure/subjectarea/asjc/2700/2711
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Depositing User: LivePure Connector
Date Deposited: 20 Apr 2022 09:30
Last Modified: 11 Jan 2023 01:21
URI: https://ueaeprints.uea.ac.uk/id/eprint/84695
DOI: 10.1007/s11897-022-00542-5


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