Conjunctival lymphoid hyperplasia presenting with bilateral panuveitis

Ioannidis, Alexander S., Rai, Poornima and Mulholland, Bridget (2005) Conjunctival lymphoid hyperplasia presenting with bilateral panuveitis. American Journal of Ophthalmology, 139 (3). pp. 566-568. ISSN 0002-9394

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PURPOSE: To report on a case of bilateral conjunctival lymphoid hyperplasia presenting with bilateral panuveitis in a female patient. DESIGN: Observational case report. METHODS: In this case excisional biopsy indicated lymphoid tissue. Immunohistochemistry showed a follicular architecture with appropriate zoning of B and T lymphocytes. RESULTS: Causes of panuveitis were considered and excluded based on a detailed history, physical examination, and laboratory investigations. The bilateral panuveitis resolved on topical corticosteroids and visual acuity returned to normal. CONCLUSIONS: Ocular adnexal lymphoproliferative lesions consist of a spectrum of disease entities, including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. There are no established clinical criteria to differentiate between these lesions. This case highlights the importance of a thorough ophthalmic examination in these patients, as an intra-ocular inflammatory process may accompany the conjunctival findings. Futhermore, we advocate periodic follow-up examinations because of the small potential risk of developing ocular or systemic lymphoma in these patients.

Item Type: Article
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Depositing User: LivePure Connector
Date Deposited: 10 Jan 2022 13:30
Last Modified: 23 Oct 2022 03:27
DOI: 10.1016/j.ajo.2004.09.024

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