International consensus statement on allergy and rhinology: Olfaction

Patel, Zara M., Holbrook, Eric H., Turner, Justin H., Adappa, Nithin, Albers, Mark W., Altundag, Aytug, Appenzeller, Simone, Costanzo, Richard M., Croy, Ilona, Davis, Greg, Dehgani-Mobaraki, Puya, Doty, Richard L., Duffy, Valerie B., Goldstein, Bradley J., Gudis, David A., Haehner, Antje, Higgins, Thomas S., Hopkins, Claire, Huart, Caroline, Hummel, Thomas, Jitaroon, Kawinyarat, Kern, Robert C., Khanwalkar, Ashoke R., Kobayashi, Masayoshi, Kondo, Kenji, Lane, Andrew P., Lechner, Matthias, Leopold, Donald A., Levy, Joshua M., Marmura, Michael J., McLelland, Lisha, Moberg, Paul J., Mueller, Cristian A., Nigwekar, Sagar U., O’Brien, Erin, Pellegrino, Robert, Philpott, Carl ORCID:, Pinto, Jayant M., Reiter, Evan R., Roalf, David R., Rowan, Nicholas R., Schlosser, Rodney J., Schwob, James, Seiden, Allen M., Smith, Timothy L., Soler, Zachary M., Sowerby, Leigh, Takaki, Miwa, Tan, Bruce K., Thamboo, Andrew, Wrobel, Bozena and Yan, Carol H. (2022) International consensus statement on allergy and rhinology: Olfaction. International Forum of Allergy & Rhinology, 12 (4). pp. 327-680. ISSN 2042-6976

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Background: The literature regarding clinical olfaction, olfactory loss, and olfactory dysfunction has expanded rapidly over the past two decades, with an exponential rise in the past year. There is substantial variability in the quality of this literature and a need to consolidate and critically review the evidence. It is with that aim that we have gathered experts from around the world to produce this International Consensus on Allergy and Rhinology: Olfaction (ICAR:O). Methods: Using previously described methodology, specific topics were developed relating to olfaction. Each topic was assigned a literature review, evidence-based review, or evidence-based review with recommendations format as dictated by available evidence and scope within the ICAR:O document. Following iterative reviews of each topic, the ICAR:O document was integrated and reviewed by all authors for final consensus. Results: The ICAR:O document reviews nearly 100 separate topics within the realm of olfaction, including diagnosis, epidemiology, disease burden, diagnosis, testing, etiology, treatment, and associated pathologies. Conclusion: This critical review of the existing clinical olfaction literature provides much needed insight and clarity into the evaluation, diagnosis, and treatment of patients with olfactory dysfunction, while also clearly delineating gaps in our knowledge and evidence base that we should investigate further.

Item Type: Article
Uncontrolled Keywords: anosmia,evidence-based medicine,hyposmia,loss of smell,olfaction,olfactory dysfunction,olfactory loss,parosmia,phantosmia,systematic review,immunology and allergy,otorhinolaryngology ,/dk/atira/pure/subjectarea/asjc/2700/2723
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Respiratory and Airways Group
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
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Depositing User: LivePure Connector
Date Deposited: 30 Nov 2021 01:44
Last Modified: 19 Oct 2023 03:11
DOI: 10.1002/alr.22929


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