The potential of breath analysis to improve outcome for patients with lung cancer

Antoniou, S. X., Gaude, E., Ruparel, M., van der Schee, M. P., Janes, S. M. and Rintoul, R. C. and LuCID research group (2019) The potential of breath analysis to improve outcome for patients with lung cancer. Journal of Breath Research, 13 (3). ISSN 1752-7155

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Lung cancer remains the most common cause of cancer related death in both the UK and USA. Development of diagnostic approaches that have the ability to detect lung cancer early are a research priority with potential to improve survival. Analysis of exhaled breath metabolites, or volatile organic compounds (VOCs) is an area of considerable interest as it could fulfil such requirements. Numerous studies have shown that VOC profiles are different in the breath of patients with lung cancer compared to healthy individuals or those with non-malignant lung diseases. This review provides a scientific and clinical assessment of the potential value of a breath test in lung cancer. It discusses the current understanding of metabolic pathways that contribute to exhaled VOC production in lung cancer and reviews the research conducted to date. Finally, we highlight important areas for future research and discuss how a breath test could be incorporated into various clinical pathways.

Item Type: Article
Uncontrolled Keywords: sdg 3 - good health and well-being ,/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
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Depositing User: LivePure Connector
Date Deposited: 30 Nov 2021 01:43
Last Modified: 03 Nov 2022 16:34
DOI: 10.1088/1752-7163/ab0bee

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