(−)-Brunneusine, a new phenolic compound with antibacterial properties in aqueous medium from the leaves of Agelanthus brunneus (Engl.) Tiegh (LORANTHACEAE)

Wieland Moifo Kuete, Thomas, Ambassa, Pantaleon, Luciane Moungang, Marlyse, Ngameni, Bathelemy, Storr, Thomas E., Ngadjui Tchaleu, Bonaventure and Stephenson, G. Richard (2021) (−)-Brunneusine, a new phenolic compound with antibacterial properties in aqueous medium from the leaves of Agelanthus brunneus (Engl.) Tiegh (LORANTHACEAE). Zeitschrift für Naturforschung C. ISSN 0939-5075

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Abstract

Agelanthus brunneus (Loranthaceae) is a hemiparasitic plant growing on Senna siamea (Fabaceae). The chemical investigation of its leaves and flowers led to the isolation of one new phenolic compound namely (-)-brunneusine (1), together with 13 known compounds. The crude leaves and flowers extracts (CLE and CFLE) with their ethyl acetate fractions (EAFL and EAFFL) and some isolated compounds (1-3; 8-9 and 11-14) have been tested on four bacterial species of sanitary importance isolated in an aquatic environment. All the samples except compound 3 showed antibacterial activity with MICs ranging from 0.43 to 8.88.103 μg/mL and MBCs from 0.43 to 3.55.103 μg/mL. Compounds 9 and 14 showed better activity on all bacterial species tested with MICs ranging from 0.43 to 27.77 μg/mL. Only CLE, EAFL and compounds 14, 2, 8 and 9 showed bactericidal effects on all bacterial species tested.

Item Type: Article
Uncontrolled Keywords: agelanthus brunneus,brunneusine,loranthaceae,antibacterial activity,biochemistry, genetics and molecular biology(all) ,/dk/atira/pure/subjectarea/asjc/1300
Faculty \ School: Faculty of Science > School of Chemistry
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Depositing User: LivePure Connector
Date Deposited: 19 Oct 2021 01:14
Last Modified: 27 Oct 2021 02:22
URI: https://ueaeprints.uea.ac.uk/id/eprint/81756
DOI: 10.1515/znc-2021-0143

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