Risk factors for depression in trauma-exposed children and adolescents: a systematic review and meta-analysis

Claxton, Jade, Vibhakar, Viktoria, Allen, Leila, Finn, Jack, Gee, Brioney and Meiser-Stedman, Richard ORCID: https://orcid.org/0000-0002-0262-623X (2021) Risk factors for depression in trauma-exposed children and adolescents: a systematic review and meta-analysis. Journal of Affective Disorders Reports, 5. ISSN 2666-9153

[thumbnail of Claxton_et_al_2021_JADR_VoR]
PDF (Claxton_et_al_2021_JADR_VoR) - Published Version
Available under License Creative Commons Attribution.

Download (993kB) | Preview


Background: While Post Traumatic Stress Disorder (PTSD) has been the most frequently studied sequela in the aftermath of trauma, post-traumatic depression is at least as prevalent, if not more so. The impacts of depression are wide-ranging, deleterious and potentially long-term. Understanding the risk factors for post-traumatic depression in children and adolescents is therefore critical. The present systematic review and meta-analysis considered this question. Method: Three databases (Medline, PsycINFO, and Published International Literature on Traumatic Stress [PILOTS]) were searched for pertinent studies. Results: Fifty-seven studies (N = 45,981) allowed for the derivation of pooled effect sizes for 12 risk factors, contributing 145 effect sizes. All effect sizes were statistically significant. Negligible to small effect sizes were largely found for pre-trauma variables (age [r=0.09], gender [r=0.16], low family income [r=0.16] and prior trauma exposure [r=0.16) and trauma-related risk factors (trauma severity [r=0.20], peri‑traumatic distress [r=0.24] and direct exposure [r=0.07]). Small to large effect sizes were found for post-trauma variables (comorbid PTSD symptoms [r=0.58], avoidant coping [r=0.26], low social support [r=0.29] and maternal depression [r=0.20]) and bereavement (r=0.29). Limitations: Risk factor effect size estimates were characterised by significant heterogeneity, and several effect sizes were based on only a few studies (e.g. income, maternal depression). Conclusions: These findings suggest that the post-traumatic responses and environments of children and adolescents may be prominent risk factors for the emergence or maintenance of post-traumatic depression in children and adolescents. This highlights potential targets for assessment and monitoring those most at risk and may also inform treatment.

Item Type: Article
Uncontrolled Keywords: adolescents,children,post-traumatic depression,risk factors,trauma,psychiatry and mental health,clinical psychology ,/dk/atira/pure/subjectarea/asjc/2700/2738
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Groups > Mental Health
Faculty of Medicine and Health Sciences > Research Centres > Lifespan Health
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 14 Apr 2021 23:53
Last Modified: 19 Oct 2023 02:56
URI: https://ueaeprints.uea.ac.uk/id/eprint/79762
DOI: 10.1016/j.jadr.2021.100150


Downloads per month over past year

Actions (login required)

View Item View Item