A cost-effective combination of Rose Bengal and off-the-shelf cationic polystyrene for the photodynamic inactivation of Pseudomonas aeruginosa

Arnau del Valle, Carla, Perez-Laguna, Vanesa, Munoz Resta, Ignacio, Gavara, Raquel, Felip-Leon, Carles, Miravet, Juan F., Rezusta, Antonio and Galindo, Francisco (2020) A cost-effective combination of Rose Bengal and off-the-shelf cationic polystyrene for the photodynamic inactivation of Pseudomonas aeruginosa. Materials Science and Engineering: C, 117. ISSN 0928-4931

Full text not available from this repository. (Request a copy)

Abstract

Two new photoactive materials have been prepared, characterized and tested against Pseudomonas aeruginosa bacteria (planktonic suspension). The synthesis of the polymeric photosensitizers can be made at a multigram scale, in few minutes, starting from inexpensive and readily available materials, such as Rose Bengal (photosensitizer) and ion exchange resins Amberlite® IRA 900 (macroporous) or IRA 400 (gel-type) as cationic polystyrene supports. The most notable feature of these systems is their notable bactericidal activity in the dark (4–5 log 10 CFU/mL reduction of the population of P. aeruginosa) which becomes enhanced upon irradiation with visible light (to reach a total reduction of 8 log 10 CFU/mL for the macroporous polymer at a fluence of 120 J/cm 2 using green light of 515 nm).

Item Type: Article
Uncontrolled Keywords: antimicrobial photodynamic inactivation,bactericidal materials,photosensitizers,rose bengal,singlet oxygen,materials science(all),condensed matter physics,mechanics of materials,mechanical engineering ,/dk/atira/pure/subjectarea/asjc/2500
Faculty \ School: Faculty of Science > School of Chemistry
Faculty of Science > School of Pharmacy
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 20 Mar 2021 00:54
Last Modified: 07 Apr 2021 01:40
URI: https://ueaeprints.uea.ac.uk/id/eprint/79510
DOI: 10.1016/j.msec.2020.111302

Actions (login required)

View Item View Item