Trajectories of pain and function in the first five years after total hip and knee arthroplasty: An analysis of patient reported outcome data from the National Joint Registry

Dainty, Jack R. ORCID: https://orcid.org/0000-0002-0056-1233, Smith, Toby ORCID: https://orcid.org/0000-0003-1673-2954, Clark, Emma M., Whitehouse, Michael R., Price, Andrew and Macgregor, Alexander ORCID: https://orcid.org/0000-0003-2163-2325 (2021) Trajectories of pain and function in the first five years after total hip and knee arthroplasty: An analysis of patient reported outcome data from the National Joint Registry. Bone & Joint Journal, 103-B (6). 1111–1118. ISSN 2049-4394

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Abstract

AIMS: To determine the trajectories of patient reported pain and functional disability over five years following total hip arthroplasty (THA) or total knee arthroplasty (TKA). METHODS: A prospective, longitudinal cohort sub-study within the National Joint Registry (NJR) was undertaken. In all, 20,089 patients who underwent primary THA and 22,489 who underwent primary TKA between 2009 and 2010 were sent Oxford Hip Score (OHS) and Oxford Knee Score (OKS) questionnaires at six months, and one, three, and five years postoperatively. OHS and OKS were disaggregated into pain and function subscales. A k-means clustering procedure assigned each patient to a longitudinal trajectory group for pain and function. Ordinal regression was used to predict trajectory group membership using baseline OHS and OKS score, age, BMI, index of multiple deprivation, sex, ethnicity, geographical location, and American Society of Anesthesiologists grade. RESULTS: Data described two discrete trajectories for pain and function: 'level 1' responders (around 70% of cases) in whom a high level of improvement is sustained over five years, and 'level 2' responders who had sustained improvement, but at a lower level. Baseline patient variables were only weak predictors of pain trajectory and modest predictors of function trajectory. Those with worse baseline pain and function tended to show a greater likelihood of following a 'level 2' trajectory. Six-month patient-reported outcome measures data reliably predicted the class of five-year outcome trajectory for both pain and function. CONCLUSION: The available preoperative patient variables were not reliable predictors of postoperative pain and function after THA and TKA. Reviewing patient outcomes at six months postoperatively is a reliable indicator of outcome at five years. Cite this article: Bone Joint J 2021;103-B(6):1111-1118.

Item Type: Article
Additional Information: Early Title: Trajectories of pain and function in the first 5 years after hip and knee joint replacement: an analysis of patient reported outcome data from the National Joint Registry of England, Wales, Northern Ireland and the Isle of Man
Uncontrolled Keywords: arthroplasty,monitoring,national registry,proms,surveillance,surgery,orthopedics and sports medicine ,/dk/atira/pure/subjectarea/asjc/2700/2746
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Faculty of Medicine and Health Sciences > School of Health Sciences
UEA Research Groups: Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging
Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Faculty of Medicine and Health Sciences > Research Groups > Nutrition and Preventive Medicine
Faculty of Medicine and Health Sciences > Research Groups > Musculoskeletal Medicine
Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health
Faculty of Science > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Groups > Norwich Epidemiology Centre
Faculty of Medicine and Health Sciences > Research Centres > Population Health
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Depositing User: LivePure Connector
Date Deposited: 03 Feb 2021 00:59
Last Modified: 19 Oct 2023 02:54
URI: https://ueaeprints.uea.ac.uk/id/eprint/79141
DOI: 10.1302/0301-620X.103B6.BJJ-2020-1437.R1

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