Vitamin K status of preterm infants with a prolonged prothrombin time

Clarke, Paul ORCID:, Mitchell, Simon J., Sundaram, Shanmuga, Sharma, Vibha, Wynn, Robert and Shearer, Martin J. (2005) Vitamin K status of preterm infants with a prolonged prothrombin time. Acta Paediatrica, International Journal of Paediatrics, 94 (12). pp. 1822-1824. ISSN 0803-5253

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Aim: To investigate the vitamin K status of preterm infants who have a prolonged prothrombin time (PT) in the first month of life. Methods: Measures of vitamin K status were assessed in 21 preterm infants who were found to have an abnormal PT, despite 0.2-0.5 mg vitamin K1 prophylaxis at birth. Results: All infants had normal or supraphysiological vitamin K1 concentrations and undetectable or, in one infant, insignificant PIVKA-II, indicating adequate vitamin K status. Conclusion: In preterm infants born at < 32 wk gestation who received ≥ 0.2 mg vitamin K1 after delivery, a prolonged PT in the first month of life is unlikely to be due to vitamin K deficiency.

Item Type: Article
Uncontrolled Keywords: phylloquinone,pivka-ii,premature,pediatrics, perinatology, and child health ,/dk/atira/pure/subjectarea/asjc/2700/2735
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Depositing User: LivePure Connector
Date Deposited: 19 Oct 2020 23:59
Last Modified: 22 Oct 2022 07:19
DOI: 10.1080/08035250500268233

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