Skin antisepsis in the neonate:What should we use?

Ponnusamy, Vennila, Venkatesh, Vidheya and Clarke, Paul ORCID: (2014) Skin antisepsis in the neonate:What should we use? Current Opinion in Infectious Diseases, 27 (3). pp. 244-250. ISSN 0951-7375

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PURPOSE OF REVIEW: Neonates in intensive care are more susceptible to sepsis. Infection is commonly acquired via the transcutaneous portal. It is necessary to identify the most effective yet safest topical antiseptics for use in neonates to reduce nosocomial sepsis. RECENT FINDINGS: Recent national surveys indicate that a wide range of topical antiseptic preparations are used in the neonatal nursery. There are very few comparative studies in neonates and no robust evidence in favour of any particular antiseptic. There are significant safety and potential toxicity issues for neonates with all the commonly used antiseptics, particularly in very small immature babies. There are no convincing roles for routine application of emollient creams on the skin, topical antiseptics on the umbilical stump, or maternal vaginal washes with chlorhexidine for the prevention of neonatal infection. SUMMARY: Large multicentre trials are needed to determine the optimal antiseptic to use for neonates undergoing intensive care, especially for extremely preterm infants.

Item Type: Article
Uncontrolled Keywords: catheter-related sepsis,coagulase-negative staphylococcus,extraluminal colonization,nosocomial sepsis,percutaneous central venous catheters,microbiology (medical),infectious diseases,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2726
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Depositing User: LivePure Connector
Date Deposited: 16 Oct 2020 23:57
Last Modified: 22 Oct 2022 07:18
DOI: 10.1097/QCO.0000000000000064

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