Standardized multi-vendor compositional MRI of knee cartilage: a key step towards clinical translation?

MacKay, James, Roemer, Frank W. and Kogan, Feliks (2020) Standardized multi-vendor compositional MRI of knee cartilage: a key step towards clinical translation? Osteoarthritis and Cartilage, 28 (12). pp. 1497-1500. ISSN 1063-4584

[img] PDF (Accepted_Manuscript) - Submitted Version
Restricted to Repository staff only until 31 August 2021.

Download (571kB) | Request a copy

Abstract

Cartilage compositional magnetic resonance imaging (MRI) techniques are sensitive to changes in the composition of the extracellular matrix of articular cartilage. Their promise lies in the potential to detect the earliest stages of cartilage degeneration, at a stage where these changes may still be reversible. This is a considerable advantage over conventional (structural) MRI; even with the high spatial-resolution imaging offered by modern high-field (3T) MRI systems, by the time structural cartilage damage is apparent, there is (by definition) damage to the collagen matrix implying that the changes are probably already irreversible.

Item Type: Article
Uncontrolled Keywords: cartilage,imaging biomarker,magnetic resonance imaging,osteoarthritis,rheumatology,biomedical engineering,orthopedics and sports medicine ,/dk/atira/pure/subjectarea/asjc/2700/2745
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 02 Sep 2020 23:54
Last Modified: 04 Dec 2020 00:44
URI: https://ueaeprints.uea.ac.uk/id/eprint/76731
DOI: 10.1016/j.joca.2020.08.007

Actions (login required)

View Item View Item