Smoking in spondyloarthritis: Unravelling the complexities

Zhao, Sizheng Steven, Goodson, Nicola J, Robertson, Selina and Gaffney, Karl ORCID: (2020) Smoking in spondyloarthritis: Unravelling the complexities. Rheumatology, 59 (7). pp. 1472-1481. ISSN 1462-0324

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Tobacco smoking is a major threat to health. There is no doubt about the need to promote and support cessation at every opportunity. Smoking has a clear role in RA, but what evidence is there that the same relationship exists in SpA? In this review, we examine (the less cited) paradoxes and contradictions in the existing axial SpA (axSpA) and PsA literature; for example, smoking appears to be 'protective' for some axSpA manifestations. We also highlight findings from higher quality evidence: smoking is associated with increased risk of PsA and the risk of psoriasis in axSpA. The relationship between smoking and SpA is far from simple. Our aim is to highlight the harms of smoking in SpA and bring attention to inconsistencies in the literature to inform further research.

Item Type: Article
Additional Information: © The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email:
Uncontrolled Keywords: ankylosing spondylitis,arthritis,axial spondyloarthritis,extra-articular manifestations,observational studies,psoriasis,psoriatic arthritis,smoking,tobacco,uveitis,rheumatology,pharmacology (medical) ,/dk/atira/pure/subjectarea/asjc/2700/2745
Faculty \ School: Faculty of Medicine and Health Sciences > Norwich Medical School
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 26 Aug 2020 00:01
Last Modified: 23 Oct 2022 02:08
DOI: 10.1093/rheumatology/keaa093

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