Using a real-world network to model localized COVID-19 control strategies

Firth, Josh A., Hellewell, Joel, Klepac, Petra, Kissler, Stephen, Kucharski, Adam J. and Spurgin, Lewis G. (2020) Using a real-world network to model localized COVID-19 control strategies. Nature Medicine. ISSN 1078-8956

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Abstract

Case isolation and contact tracing can contribute to the control of COVID-19 outbreaks1,2. However, it remains unclear how real-world social networks could influence the effectiveness and efficiency of such approaches. To address this issue, we simulated control strategies for SARS-CoV-2 transmission in a real-world social network generated from high-resolution GPS data that were gathered in the course of a citizen-science experiment3,4. We found that tracing the contacts of contacts reduced the size of simulated outbreaks more than tracing of only contacts, but this strategy also resulted in almost half of the local population being quarantined at a single point in time. Testing and releasing non-infectious individuals from quarantine led to increases in outbreak size, suggesting that contact tracing and quarantine might be most effective as a ‘local lockdown’ strategy when contact rates are high. Finally, we estimated that combining physical distancing with contact tracing could enable epidemic control while reducing the number of quarantined individuals. Our findings suggest that targeted tracing and quarantine strategies would be most efficient when combined with other control measures such as physical distancing.

Item Type: Article
Faculty \ School: Faculty of Science > School of Biological Sciences
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 10 Aug 2020 23:52
Last Modified: 22 Sep 2020 23:54
URI: https://ueaeprints.uea.ac.uk/id/eprint/76377
DOI: 10.1038/s41591-020-1036-8

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