Clinical and cost effectiveness of a multi-professional medication reviews in care homes (CAREMED)

Desborough, James ORCID: https://orcid.org/0000-0001-5807-1731, Clark, Allan ORCID: https://orcid.org/0000-0003-2965-8941, Houghton, Julie, Sach, Tracey ORCID: https://orcid.org/0000-0002-8098-9220, Shaw, Val, Kirthisingha, Viveca, Holland, Richard and Wright, David (2020) Clinical and cost effectiveness of a multi-professional medication reviews in care homes (CAREMED). International Journal of Pharmacy Practice, 28 (6). pp. 626-634. ISSN 0961-7671

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Abstract

Objectives With 70% of care home residents experiencing a medication error every day in the UK, better multi‐professional working between medical practitioners, pharmacists and care homes was recommended. The aim of this study was to determine the effectiveness (falls reduction) and cost‐effectiveness, of a multi‐professional medication review (MPMR) service in care homes for older people. Method A total of care homes in the East of England were cluster randomised to ‘usual care’ or two multi‐professional (General practitioner, clinical pharmacist and care homes staff) medication reviews during the 12‐month trial period. Target recruitment was 900 residents with 10% assumed loss to follow‐up. Co‐primary outcome measures were number of falls and potentially inappropriate prescribing assessed by the Screening Tool of Older Persons Prescriptions. Key findings A total of 826 care home residents were recruited with 324 lost to follow‐up for at least one primary outcome measure. The mean number of falls per resident per annum was 3.3 for intervention and 3.0 for control (P = 0.947). Each resident was found to be prescribed 0.69 (intervention) and 0.85 (control) potentially inappropriate medicines after 12 months (P = 0.046). No significant difference identified in emergency hospital admissions or deaths. Estimated unadjusted incremental mean cost per resident was £374.26 higher in the intervention group. Conclusions In line with other medication review based interventions in care homes, two MPMRs improved medication appropriateness but failed to demonstrate improvements in clinical outcomes. From a health system perspective costs where estimated to increase overall and therefore a different model of medicines management is required.

Item Type: Article
Uncontrolled Keywords: nursing homes,medication safety,pharmacists,health services research,public health, environmental and occupational health,health policy,pharmacy,pharmaceutical science,sdg 3 - good health and well-being ,/dk/atira/pure/subjectarea/asjc/2700/2739
Faculty \ School: Faculty of Science > School of Pharmacy (former - to 2024)
Faculty of Medicine and Health Sciences > Norwich Medical School
UEA Research Groups: Faculty of Science > Research Groups > Patient Care
Faculty of Science > Research Groups > Innovations in Pharmacy Education
Faculty of Medicine and Health Sciences > Research Groups > Public Health and Health Services Research (former - to 2023)
Faculty of Medicine and Health Sciences > Research Groups > Norwich Clinical Trials Unit
Faculty of Medicine and Health Sciences > Research Groups > Health Services and Primary Care
Faculty of Medicine and Health Sciences > Research Groups > Epidemiology and Public Health
Faculty of Medicine and Health Sciences > Research Groups > Rehabilitation
Faculty of Medicine and Health Sciences > Research Groups > Health Promotion
Faculty of Medicine and Health Sciences > Research Groups > Health Economics
Faculty of Medicine and Health Sciences > Research Centres > Norwich Institute for Healthy Aging
Faculty of Medicine and Health Sciences > Research Centres > Population Health
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Depositing User: LivePure Connector
Date Deposited: 16 Jul 2020 23:47
Last Modified: 25 Sep 2024 14:51
URI: https://ueaeprints.uea.ac.uk/id/eprint/76156
DOI: 10.1111/ijpp.12656

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