Antibacterial constituents of Neohyptis paniculata

Rahman, M. Mukhlesur and Gibbons, Simon (2015) Antibacterial constituents of Neohyptis paniculata. Fitoterapia, 105. pp. 269-272. ISSN 0367-326X

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A new α-pyrone, 6R-[5R,6S-diacetyloxy-1Z,3E-heptadienyl]-5,6-dihydro-2H-pyran-2one (1), along with six known compounds including an α-pyrone, flavones and terpenes was isolated from the aerial parts of Neohyptis paniculata. The structure of 1 was established unambiguously by MS and a series of 1D and 2D-NMR spectroscopic analyses. The antibacterial activity of the compounds (1-7) was investigated against five strains of multi-drug resistant (MDR) and methicillin-resistant Staphylococcus aureus and minimum inhibitory concentrations (MICs) of these compounds were found to be in the range of 64-256 μg/mL.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy
Depositing User: LivePure Connector
Date Deposited: 14 Jul 2020 23:51
Last Modified: 04 Mar 2024 17:57
DOI: 10.1016/j.fitote.2015.07.012

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