Clerodane diterpenes from the bark of Casearia tremula

Gibbons, Simon, Gray, Alexander I. and Waterman, Peter G. (1996) Clerodane diterpenes from the bark of Casearia tremula. Phytochemistry, 41 (2). pp. 565-570. ISSN 0031-9422

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Abstract

Six novel clerodane diterpenes have been isolated from the bark of Casearia tremula. They were characterized by extensive use of Heteronuclear Multiple Bond Coherence NMR spectroscopy as rel-18(S),19(R)-diacetoxy-18,19-epoxy-6(R)-methoxy-2(S)-(2ξ-methylbutanoyloxy)5(R),8(S),9(S),10(R)-cleroda-3,13(16),14-triene, rel-18(S),19(R)-diacetoxy-18,19-epoxy-2(S)-(2ξ-methylbutanoyloxy)-5(R),8(S),9(S),10(R)-cleroda-3,13(16),14-triene, rel-18(S),19(R)-diacetoxy-18,19-epoxy-2(R)-hexanoyloxy-5(R),8(S),9(S),10(R)-cleroda-3,13(16),14-triene, rel-18(S),19(R)-diacetoxy-18,19-epoxy-6(R)-hydroxy-2(S)-octanoyloxy-5(R),8(S),9(S),10(R)-cleroda-3,13(16),14-triene and rel-18(S),19(R)-diacetoxy-18,19-epoxy-6(R)-hydroxy-2(S)-undecanoyloxy-5(R),8(S),9(S),10(R)-cleroda-3,13(16),14-triene, rel-18(S),19(R)-diacetoxy-18,19-epoxy-6(R)-hydroxy2(S)-(2ξ-methylbutanoyloxy)-5(R),8(S),9(S),10(R)-cleroda-3,13(16),14-triene and rel-18(S),19(R)-diacetoxy-18,19-epoxy-6(R)-hydroxy-2(S)-(3ξ-hydroxyoctanoyloxy)-5(R),8(S),9(S), 10(R)-cleroda-3,13(16),14-triene.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 10 Jul 2020 00:08
Last Modified: 10 Jul 2020 00:08
URI: https://ueaeprints.uea.ac.uk/id/eprint/76007
DOI: 10.1016/0031-9422(95)00623-0

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