Interventions for reducing hospital-associated deconditioning: a systematic review and meta-analysis

Smith, Toby ORCID:, Sreekanta, Ashwini, Walkeden, Sarah, Penhale, Bridget ORCID: and Hanson, Sarah ORCID: (2020) Interventions for reducing hospital-associated deconditioning: a systematic review and meta-analysis. Archives of Gerontology and Geriatrics, 90. ISSN 0167-4943

[thumbnail of HADS_SystematicReview_MS_V1.1_02July2020_accepted]
PDF (HADS_SystematicReview_MS_V1.1_02July2020_accepted) - Accepted Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.

Download (537kB) | Preview


Purpose: To determine the effectiveness of hospital-based interventions designed to reduce Hospital-Associated Deconditioning (HAD) for people in inpatient hospital settings. Materials & Methods: Systematic literature search of published and unpublished databases was conducted from (inception to 01 June 2020). Randomised and non-randomised controlled trials investigating the effectiveness of enhanced inpatient programmes aimed to reduce HAD in adults admitted to a hospital ward were included. Evidence was appraised using the Cochrane Risk of Bias tool and outcomes evaluated against the GRADE criteria. Where appropriate, data were pooled in meta-analyses and presented as risk difference (RD) or standardised mean difference with 95% confidence intervals (CI). Results: Seven studies recruiting 12,597 participants (7864 enhanced programmes; 4349 usual care) were included. There was low-quality evidence for reduced risk of decline in physical performance for those in the enhanced programmes compared to usual care (RD: -0.04; 95% CI: -0.08 to -0.01; N=2085). There was low- or very-low quality evidence reporting no benefit of enhanced programmes for mobility on discharge, length of hospital stay, hospital readmission, and mortality within the first three-months post-admission (p>0.05). There was low-quality evidence that nursing home placement and mortality at 12-months was superior through enhanced inpatient programmes compared to usual care. Conclusion: Enhanced inpatient programmes targeted at HAD may offer benefit over usual care for some outcomes. There remain uncertainty in relation to how applicable the findings are to non-North American countries, which elements of an enhanced programme are most important to reduce HAD, and longer-term sequelae.

Item Type: Article
Uncontrolled Keywords: inpatient,deconditioning,physical inactivity,bed rest,frailty,ward intervention
Faculty \ School: Faculty of Medicine and Health Sciences > School of Health Sciences
Related URLs:
Depositing User: LivePure Connector
Date Deposited: 03 Jul 2020 23:58
Last Modified: 22 Oct 2022 06:26
DOI: 10.1016/j.archger.2020.104176

Actions (login required)

View Item View Item