New constituents of Artemisia monosperma

Stavri, Michael, Mathew, K. Thomas, Gibson, Trevor, Williamson, R. Thomas and Gibbons, Simon (2004) New constituents of Artemisia monosperma. Journal of Natural Products, 67 (5). pp. 892-894. ISSN 0163-3864

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A new eudesmane sesquiterpene (1) and a C10 diyne (2) were isolated from the aerial parts of Artemisia monosperma. The structures of these compounds were determined as rel-1β,3α,6β-trihydroxyeudesm-4-ene (1) and 1,3R,8R-trihydroxydec-9-en-4,6-yne (2) on the basis of spectral data interpretation. The absolute stereochemistry of 2 was determined using Mosher ester methodology in which the terminal primary hydroxyl group was first protected to simplify the stereochemical analysis.

Item Type: Article
Faculty \ School: Faculty of Science > School of Pharmacy
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Depositing User: LivePure Connector
Date Deposited: 01 Jul 2020 00:01
Last Modified: 04 Mar 2024 17:56
DOI: 10.1021/np030558v

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