Phytochemistry and antimycobacterial activity of Chlorophytum inornatum

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O’Donnell, Gemma, Bucar, Franz and Gibbons, Simon (2006) Phytochemistry and antimycobacterial activity of Chlorophytum inornatum. Phytochemistry, 67 (2). pp. 178-182. ISSN 0031-9422

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Abstract

In a project to investigate plant derived natural products from the Liliaceae with activity against fast-growing strains of mycobacteria, we have identified two new metabolites from Chlorophytum inornatum. The active principle, a new homoisoflavanone (1) was identified as 3-(4′-methoxybenzyl)-7,8-methylenedioxy-chroman-4-one. The metabolite assigned as 7-(1′-hydroxyethyl)-2-(2″-hydroxyethyl)-3,4-dihydrobenzopyran (2) was characterised by extensive 1- and 2D NMR spectroscopy. The antimycobacterial activity of this plant was mainly due to the homoisoflavonoid which exhibited minimum inhibitory values ranging from 16–256 μg/ml against four strains of fast-growing mycobacteria.

Item Type:	Article
Faculty \ School:	Faculty of Science > School of Pharmacy
Related URLs:	https://linkinghub.elsevier.com/retrieve...
Depositing User:	LivePure Connector
Date Deposited:	27 Jun 2020 00:02
Last Modified:	22 Oct 2022 06:23
URI:	https://ueaeprints.uea.ac.uk/id/eprint/75797
DOI:	10.1016/j.phytochem.2005.10.023

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